Print this page Email this page
Users Online: 286
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
CASE REPORT
Year : 2019  |  Volume : 9  |  Issue : 2  |  Page : 50-52

Malignant periperal nerve sheath tumor of the breast in a patient with neurofibroma type 1: An unusual presentation


1 Department of Surgery, Abubakar Tafawa Balewa University Teaching Hospital, Bauchi, Nigeria
2 Deparment of Surgery, Aminu Kano Teaching Hospital, Kano, Nigeria

Correspondence Address:
Dr. Ibrahim U Garzali
Department of Surgery, Abubakar Tafawa Balewa University Teaching Hospital, Bauchi
Nigeria
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ais.ais_9_20

Rights and Permissions

Breast cancer of mesenchymal origin is rare. Malignant peripheral nerve sheath tumors (MPNST) are believed to derived from peripheral nerves or demonstrate peripheral nerve differentiation. They represent only 5-10% of all malignant soft tissue sarcomas with an incidence of 4% in patients with neurofibromatosis type 1 syndrome and 0.001% in general population. We present a 40-year-old woman with Von Recklinghausen's disease diagnosed 10 years prior to presentation and complain of right breast lump of 3 months duration that rapidly increase to affect the whole breast. The overlying skin ulcerated spontaneously with preservation of the nipple areola complex. Examination revealed features of Neurofibromatosis type 1. The right breast contained a hard mass with an overlying ulcer. Axillary lymph nodes were not enlarged. Incisional biopsy of the ulcer revealed features of neurofibromatosis. A chest radiograph revealed pleural effusion while abdominal ultrasound revealed liver metastasis. A diagnosis of metastatic peripheral nerve sheath tumour was made. The challenges in the diagnosis and treatment of this patient are discussed.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed135    
    Printed10    
    Emailed0    
    PDF Downloaded36    
    Comments [Add]    

Recommend this journal