AU - Abubakar, B AU - Abubakar, A AU - Tela, U AU - Gabchiya, M AU - Isah, M AU - Dogo, H AU - Panti, A AU - Ogunyele, T TI - An appraisal on antibiotic susceptibility of common bacterial pathogens in urinary tract infections at a Nigerian Tertiary Health Center PT - ORIG DP - 2017 Apr 1 TA - Archives of International Surgery PG - 56-61 VI - 7 IP - 2 4099- https://www.archintsurg.org/article.asp?issn=2278-9596;year=2017;volume=7;issue=2;spage=56;epage=61;aulast=Abubakar;type=0 4100- https://www.archintsurg.org/article.asp?issn=2278-9596;year=2017;volume=7;issue=2;spage=56;epage=61;aulast=Abubakar AB - Background: Urinary tract infections (UTIs) with concomitant rise in antibiotic resistance among uropathogens remained a major health problem. A periodic appraisal of the microbial agents responsible for UTIs with their antimicrobial susceptibility is, therefore, fundamental for a fitted empirical antimicrobial intervention. This study determined the range of bacterial species in patients with suspected UTI and their antibiotic susceptibility pattern at a tertiary care center in Nigeria. Patients and Methods: This was a retrospective review of urine samples subjected to microscopy, culture, and sensitivity from patients with suspected UTI in 2015. Bacterial isolates were identified by biochemical profiling. The antibiotics susceptibility of the culture-positive isolates was achieved by disk diffusion method as recommended in the Clinical Laboratory Standard Institute guidelines. Results: There were 1,096 urine samples subjected to microscopy, culture, and sensitivity during the study period; 1,001 met the inclusion criteria. Urine microscopy yielded significant pyuria in 23.2% and sterile pyuria in 8%. Urine culture was positive in 43% of the specimens and yielded Escherichia coli in 28%, Staphylococcus aureus was seen in 6.1%, and Klebsiella in 4.8%. Out of the positive cultures, 35.3% specimens have significant pyuria. The most sensitive antibiotics were Streptomycin, Ciprofloxacin, and Gentamycin. Resistance was predominantly to Nalidixic acid, Ceftriaxone, and Ampicillin. Conclusion: Periodic appraisal of the uropathogens and evaluation of their sensitivity is a needed guide in empirical antibiotic interventions. In this appraisal, E. coli was the commonest agents in patients with UTI. Most of the microbes were sensitive to Aminoglycoside and Ciprofloxacin but often resistant to Nalidixic acid and Ceftriaxone.