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Year : 2020  |  Volume : 10  |  Issue : 2  |  Page : 57-62

Cutaneous squamous cell carcinoma of the neck: Dramatic response to cytotoxic chemotherapy or spontaneous regression?

1 Department of Surgery, A.B.U. Teaching Hospital, Zaria, Nigeria
2 Department of Pathology and Morbid Anatomy, A.B.U. Teaching Hospital, Zaria, Nigeria

Correspondence Address:
Dr. M Daniyan
Department of Surgery, A.B.U. Teaching Hospital, Zaria
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ais.ais_29_20

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Skin cancers are common worldwide though incidence is higher among Caucasians. While basal cell carcinoma (BCC) is more common among Caucasians, squamous cell carcinoma (SCC) is the most common non-melanoma skin cancer in Nigeria as well as in other African countries.The Standard of care remains surgical resection with preservation of function and cosmesis, followed by adjuvant radiotherapy. Occasionally, however, systemic chemotherapy may be indicated. When it is, Cisplatin-based regimen has been the standard of care. We hereby report two cases of high risk cutaneous SCC with a dramatic response to preoperative Cisplatin/Methotrexate combination chemotherapy and highlight the possibility of spontaneous regression of SCC.

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